"Hypoallergenic" - Definition: non-allergy producing. A term applied to a preparation in which every possible care has been taken in formulation and production to ensure minimum instance of allergic reaction. (source: Blakiston's medical Dictionary)
There are four basic requirements for manufacturing a truly hypoallergenic product:
1. Actually being a manufacturer
Thorne Research is a manufacturer, not just a sales or distribution company. The most important words to look for on any dietary supplement product label are “Manufactured By.” Thorne Research products are manufactured to exact specifications by our production staff, in our own state-of-the-art facility. Mixing and encapsulating are done in separate, sealed, individually-ventilated rooms with filtered air, to ensure there is no cross-contamination of materials. From the mixing of raw materials to packaging and labeling, numerous quality control checks are made before the finished product is released for sale.
2. Raw material choice
To produce our truly hypoallergenic encapsulated supplements, we use only the purest raw materials available. Every manufacturer has two basic choices available for raw materials: purchase either truly pure raw materials, or purchase raw materials to which substances have been added to facilitate manufacturing. Typical choices every manufacturer must make are: purchase pure vitamin C or purchase vitamin C with additives; purchase pure B vitamins or purchase coated B vitamins for taste masking, purchase pure enzymes such as pancreatin, pepsin and bromelain, or purchase enzymes diluted with lactose.
3. Avoiding Unnecessary Ingredients
Tablets must contain flowing agents, lubricants, binders, fillers, and disintegrants in order to be made into tablets. Encapsulated products are not free from these kinds of ingredients either. Lubricants such as stearic/palmitic acid, labeled also as magnesium stearate or calcium stearate, or sometimes ascorbyl palmitate are employed by almost all manufacturers, as are diluents such as lactose, dextrose, sucrose, and corn starch.
4. Quality Control
Since 1984, Thorne Research has been dedicated to providing the practitioner with the best nutritional supplements in the world. As an adjunct to this mission, we utilize an in-house quality control laboratory, as well as outside, independent laboratories. Near-infrared spectrophotometry (NIRS), atomic absorption spectrophotometry, inductively coupled plasma technology, or high performance liquid chromatography (HPLC) are used to check every raw material purchased, every mineral we manufacture, and every finished product before it is released for sale. These items are assayed for purity, quality, heavy metals, and potency. Those materials that do not meet our rigid specifications are rejected. In addition, products are sent to an independent lab for microbial analysis, and fatty acids (including fish oils) are sent out for pesticide analysis.
